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J Audiol Otol > Epub ahead of print
DOI: https://doi.org/10.7874/jao.2018.00276    [Epub ahead of print] Published online December 7, 2018.
Single Dose Topical Application of Clotrimazole for the Treatment of Otomycosis: Is This Enough?
Rıza Dundar1, İsmail İynen2
1Department of Otorhinolaryngology, Vocational School of Health Scienses, Acıbadem Mehmet Ali Aydınlar University, Eskis¸ ehir Hospital, Eskis¸ ehir, Turkey
2Department of Otorhinolaryngology, Harran University, S¸ anlıurfa, Turkey
Correspondence  Rıza Dundar ,Tel: +90 5304199225, Fax: +90 (222) 3300100, Email: dundarkbb2@gmail.com
Submitted: June 13, 2018  Accepted after revision: August 14, 2018
Background and Objectives
To determine the efficacy of filling the external auditory meatus with 1% clotrimazole at a single visit for the treatment of otomycosis.
Subjects and Methods
This prospective study included 40 patients who were referred to our clinic with complaints of ear itching, pain, and fullness, and were diagnosed with unilateral otomycosis. After cleaning the mycotic hyphae from the external auditory meatus, the ear canal was filled with 1% clotrimazole, using an intravenous catheter and syringe. The patients received follow-up examinations on post-treatment days 7, 15, and 45.
The follow-up otomicroscopic examinations revealed that 95% of the ear canals were entirely clean and that all symptoms had resolved. The post-treatment scores of pain, aural fullness and itching were significantly lower than the pre-treatment scores (p<0.01).
Filling the external auditory meatus with 1% clotrimazole at a single visit is an easy, efficient, and cost-effective treatment for otomycosis. Additionally, high patient compliance makes this treatment superior to long-term topical therapy.
Keywords: Otomycosis · Topical treatment · Clotrimazole
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